Depot haloperidol decanoate for schizophrenia

The influence of renal impairment on the pharmacokinetics of haloperidol has not been evaluated. About one-third of a haloperidol dose is excreted in urine, mostly as metabolites. Less than 3% of administered haloperidol is eliminated unchanged in the urine. Haloperidol metabolites are not considered to make a significant contribution to its activity, although for the reduced metabolite of haloperidol, back-conversion to haloperidol cannot be fully ruled out. Even though impairment of renal function is not expected to affect haloperidol elimination to a clinically relevant extent, caution is advised in patients with renal impairment, and especially those with severe impairment, due to the long half-life of haloperidol and its reduced metabolite, and the possibility of accumulation (see section ).

A 2005 paper suggested leuprorelin as a possible treatment for autism , [19] the hypothetical method of action being the now defunct hypothesis that autism is caused by mercury , with the additional unfounded assumption that mercury binds irreversibly to testosterone and therefore leuprorelin can help cure autism by lowering the testosterone levels and thereby mercury levels. [20] However, there is no scientifically valid or reliable research to show its effectiveness in treating autism. [21] This use has been termed the "Lupron protocol" [22] and Mark Geier , the proponent of the hypothesis, has frequently been barred from testifying in vaccine-autism related cases on the grounds of not being sufficiently expert in that particular issue [23] [24] [25] and has had his medical license revoked. [22] Medical experts have referred to Geier's claims as "junk science". [26]

processing.... Drugs & Diseases haloperidol (Rx) Brand and Other Names: Haldol, Haldol Decanoate, more... Haloperidol LA, Peridol

  • Classes: Antipsychotics, 1st Generation
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Sections haloperidol (Rx)
  • Sections haloperidol
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Dosing & Uses Adult Pediatric Geriatric Dosage Forms & Strengths tablet

Depot haloperidol decanoate for schizophrenia

depot haloperidol decanoate for schizophrenia

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