processing.... Drugs & Diseases haloperidol (Rx) Brand and Other Names: Haldol, Haldol Decanoate, more... Haloperidol LA, Peridol
Pregnancy category C: Haloperidol crosses the placenta, and adverse events have been reported in animal reproduction studies. Although haloperidol has not been proven to be a major human teratogen, there are concerns with use in pregnancy, and an association with limb abnormalities following first trimester exposure cannot be ruled out [ 11]. Use during third trimester is also problematic, and may cause extrapyramidal symptoms and withdrawal symptoms in newborns following delivery. Haloperidol is excreted in breast milk, and breast-feeding is not recommended [ 1].
The intravenous route is not FDA approved and is generally not recommended except when no other alternatives are available. Intravenous administration appears to be associated with a higher risk of QT prolongation and torsade de pointes (TdP) than other forms of administration. The manufacturer recommends ECG monitoring for QT prolongation and arrhythmias if IV administration is required. A dose in the range of 1 to 5 mg IV has been suggested, with the dose being repeated at 30 to 60 minute intervals, if needed. A maximum IV dose has not been established. The lowest effective dose should be used in conjunction with conversion to oral therapy as soon as possible.