In observance of Women's History Month 2017, DPIC staff members Anne Holsinger and Robin Konrad interviewed Mary Atwell, ., one of the nation’s foremost experts on women on death row. Dr. Atwell is Professor Emerita of Criminal Justice at Radford University and author of three books on capital punishment, most recently Wretched Sisters: Examining Gender and Capital Punishment . The podcast discusses Dr. Atwell's research and highlights the themes and patterns present in capital murder cases in which women were the defendants. Running time: 41:06 (March 24, 2017)
In normal volunteers, single intravenous doses of mg/kg of ondansetron had no effect on esophageal motility, gastric motility, lower esophageal sphincter pressure, or small intestinal transit time. In another trial in six normal male volunteers, a 16-mg dose infused over 5 minutes showed no effect of the drug on cardiac output , heart rate, stroke volume , blood pressure, or electrocardiogram ( ECG ). Multiday administration of ondansetron has been shown to slow colonic transit in normal volunteers. Ondansetron has no effect on plasma prolactin concentrations. In a gender-balanced pharmacodynamic trial (n = 56), ondansetron 4 mg administered intravenously or intramuscularly was dynamically similar in the prevention of nausea and vomiting using the ipecacuanha model of emesis .
Fentanyl produces respiratory depression by direct action on brain stem respiratory centers. The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and electrical stimulation. Fentanyl causes miosis, even in total darkness. Pinpoint pupils are a sign of opioid overdose but are not pathognomic (., pontine lesions of hemmorhagic or ischemic origins may produce similar findings). Marked mydriasis rather than miosis may be seen due to hypoxia in overdose situations.