Most drugs of abuse are addictive. Addiction is a chronic, relapsing disease characterized by compulsive drug seeking and use despite negative consequences and by long-lasting changes in the brain. People who are addicted have strong cravings for the drug, making it difficult to stop using. Most drugs alter a person’s thinking and judgment, which can increase the risk of injury or death from drugged driving or infectious diseases (., HIV/AIDS, hepatitis) from unsafe sexual practices or needle sharing. Drug use during pregnancy can lead to neonatal abstinence syndrome, a condition in which a baby can suffer from dependence and withdrawal symptoms after birth. Pregnancy-related issues are listed in the chart below for drugs where there is enough scientific evidence to connect the drug use to negative effects. However, most drugs could potentially harm an unborn baby.
Note that in androgen-responsive target tissues such as the skin, scalp, and prostate, the relative androgenicity of nandrolone is reduced by its reduction to dihydronandrolone (DHN). 438 439 The 5-alpha reductase enzyme is responsible for this metabolism of nandrolone. The concurrent use of a 5-alpha reductase inhibitor such as finasteride or dutasteride will interfere with site-specific reduction of nandrolone action, considerably increasing the tendency of nandrolone to produce androgenic side effects. Reductase inhibitors should be avoided with nandrolone if low androgenicity is desired.
Among the widely used steroids is Deca-Durabolin. For the past three decades, Deca Durabolin steroid has delivered great gains to people looking for muscle mass and has the ability to reduce joint pain and boost the body’s immune system. The most important benefit of Deca-Durabolin for both amateur athletes and bodybuilders is that it doesn’t have serious side effects since it doesn’t convert to estrogen like other compounds. As such, Deca-Durabolin does not have severe or higher degree side effects that other compounds might have.