Increased bleeding risk: If you have any medical conditions that may cause an increased risk of bleeding, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. These conditions include uncontrolled very high blood pressure; a problem with the blood vessels in the back of the eye called retinopathy ; current or past ulcer of the stomach or intestines; recent stroke; or recent surgery of the brain, spinal column, or eye.
The absolute bioavailability of apixaban is approximately 50% for doses up to 10 mg of ELIQUIS. Food does not affect the bioavailability of apixaban. Maximum concentrations (Cmax) of apixaban appear 3 to 4 hours after oral administration of ELIQUIS. At doses ≥ 25 mg, apixaban displays dissolutionlimited absorption with decreased bioavailability. Following oral administration of 10 mg of apixaban as 2 crushed 5 mg tablets suspended in 30 mL of water, exposure was similar to that after oral administration of 2 intact 5 mg tablets. Following oral administration of 10 mg of apixaban as 2 crushed 5 mg tablets mixed with 30 g of applesauce, the Cmax and AUC were 20% and 16% lower, respectively, when compared to administration of 2 intact 5 mg tablets. Following administration of a crushed 5 mg ELIQUIS tablet that was suspended in 60 mL D5W and delivered through a nasogastric tube , exposure was similar to that seen in other clinical trials involving healthy volunteers receiving a single oral 5 mg tablet dose.
Second of all she lost a lot of weight in her hospital stay and I have read that people less than 60 kg of weight should take only 2 1 / 2 of apixaban, my wife is under her weight she weighs 37 kg and is on 5 mg 2 times a day also she’d been losing a lot of her hair and she has only been taking this poison for 7 weeks and supposedly she should take it for 12 weeks I am very desperate and I do not see the time that this damn poison is out of her system. all doctors nurses even the GP agree that this poison apixaban does not do that therefore so I told the please someone explains to me where all those evils side effects come 20 minutes after my wife takes apixaban all these uncommon that’s how they call uncommon side effects coming from .